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| Symbol | ATP1B2 |
| Full Name | ATPase Na+/K+ Transporting Subunit Beta 2 |
| Chromosome | 17p13.1 |
| NCBI Gene | 481 |
| OMIM | 182360 |
| Ensembl | ENSG00000129226 |
| UniProt | P14415 |
| Associated Diseases | Glaucoma |
ATP1B2 is a gene encoding a protein involved in ion transport that plays important roles in neuronal function and has been implicated in neurodegenerative diseases.
The ATP1B2 gene encodes a protein that is part of a family of ion transporters critical for maintaining ionic homeostasis in neurons. These proteins are essential for proper neuronal excitability, calcium signaling, and cellular viability.
Ion transporters maintain the electrochemical gradients necessary for neuronal function. The ATP1B2 protein contributes to cellular homeostasis and has been studied in the context of excitotoxicity, calcium dysregulation, and neurodegenerative processes in Alzheimer's and Parkinson's disease.
ATP1B2 encodes the beta-2 subunit of Na+/K+-ATPase, primarily expressed in the nervous system. It is important for astrocyte function and neuronal potassium buffering.
ATP1B2 encodes the beta-2 subunit. Expressed in retina and brain.
Expressed in brain and retina.