Slc25A4 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Slc25A4 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
{{Infobox gene}}
SLC25A4 (Solute Carrier Family 25 Member 4, also known as ANT1) encodes a mitochondrial ADP/ATP translocase that exchanges ADP and ATP across the inner mitochondrial membrane.
| Attribute | Value |
|---|---|
| Gene Symbol | SLC25A4 |
| Full Name | Solute Carrier Family 25 Member 4 |
| Chromosomal Location | 4q34.3 |
| NCBI Gene ID | 291 |
| OMIM | 103220 |
| Ensembl ID | ENSG00000151729 |
| UniProt ID | P12235 |
SLC25A4 (ANT1) is a mitochondrial carrier protein that exchanges mitochondrial ATP for cytosolic ADP.
| Disease | Mutation Type | Inheritance | Notes |
|---|---|---|---|
| Mitochondrial Myopathy | Dominant | Autosomal | Exercise intolerance, muscle weakness |
| Progressive External Ophthalmoplegia | Dominant | Autosomal | PEO with mtDNA deletions |
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Slc25A4 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Slc25A4 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.