ADORA3 Gene is involved in circadian rhythm regulation and has been implicated in neurodegenerative diseases. This page provides information about its structure, function, and role in neurodegeneration.
ADORA3 Gene plays a critical role in the molecular circadian clock and its dysregulation may contribute to neurodegeneration.
| ADORA3 — Adenosine A3 Receptor | |
|---|---|
| Gene Symbol | ADORA3 |
| Full Name | ADORA3 — Adenosine A3 Receptor |
| Chromosome | 1p13.2 |
| NCBI Gene ID | 134 |
| OMIM | 600445 |
| Ensembl ID | ENSG00000121879 |
| UniProt ID | P0DP24 |
| Associated Diseases | Neuroinflammation, ischemia, neurodegeneration |
ADORA3 is an adenosine receptor that couples to Gi proteins and modulates cAMP levels. It is involved in immune response and neuroprotection.
ADORA3 activation has anti-inflammatory effects. Modulation of adenosine signaling may be therapeutic in neurodegeneration.
Wide tissue distribution, expressed in brain microglia and neurons.