Homer2 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
.infobox .infobox-gene
| Gene Symbol | HOMER2 |
|---|---|
| Gene Name | Homer Scaffold Protein 2 |
| Chromosome | 15q25.3 |
| NCBI Gene ID | 9457 |
| OMIM ID | 604799 |
| Ensembl ID | ENSG00000193990 |
| UniProt ID | Q9NSC1 |
| Associated Diseases | Alzheimer's Disease, Auditory Processing, Schizophrenia |
| --- | --- |
| Categories | Calcium Signaling, Synaptic Plasticity |
This section provides a comprehensive overview of the gene/protein and its role in the nervous system and neurodegenerative diseases.
Homer 2 is a postsynaptic scaffold protein that regulates metabotropic glutamate receptor signaling and calcium homeostasis. It is expressed in various brain regions including the hippocampus and cortex. HOMER2 polymorphisms are associated with schizophrenia and auditory processing deficits.
The HOMER2 gene is associated with several diseases.
The study of Homer2 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.