Dates: April 5-9, 2025
Location: Pennsylvania Convention Center, Philadelphia, Pennsylvania, USA
Organizer: American Academy of Neurology (AAN)
Website: aan.com/meetings/annual-meeting
AAN 2025 returned to Philadelphia, the birthplace of American neurology, bringing together over 14,000 neurologists and neuroscience professionals. The meeting is the world's largest gathering of neurologists, presenting advances in all areas of neurological research and clinical practice.
- Anti-amyloid monoclonal antibodies — Clinical implementation and real-world data
- Lecanemab (Leqembi) — Post-approval effectiveness
- Donanemab (Kisunla) — Clinical experience
- Tau-targeted therapies — Emerging approaches
¶ Diagnosis and Biomarkers
- Blood-based biomarkers — p-tau implementation in practice
- Neuropsychology — Cognitive assessment advances
- Neuroimaging — MRI and PET updates
- Fluid biomarkers — CSF and blood markers
- Deep brain stimulation — New targets and programming
- Levodopa formulations — Extended-release options
- Gene therapies — AAV-based approaches
- Neuroprotective agents — Disease modification strategies
- Tremor — Mechanism and treatment
- Dystonia — Botulinum toxin updates
- Huntington's disease — Therapeutic pipeline
- Ataxia — Genetic and therapeutic approaches
- Antisense oligonucleotides — SOD1 and C9orf72 programs
- Gene therapy approaches for familial ALS
- Small molecule neuroprotective agents
- Stem cell transplantation trials
- Respiratory management — Non-invasive ventilation
- Nutritional support — PEG tube management
- Speech therapy — Augmentative communication
- Multidisciplinary care models
- Lewy body dementia — Biomarkers and treatment
- Frontotemporal dementia — Genetic forms and trials
- Vascular dementia — Prevention strategies
- Primary progressive aphasia — Language variants
- Alzheimer's disease — p-tau217, p-tau181 implementation
- Parkinson's disease — NfL and alpha-synuclein assays
- Multiple sclerosis — Neurofilament monitoring
- ALS — Biomarker development
- Gene therapy for neurological disorders
- Immunotherapy targeting protein aggregates
- Small molecule disease modifiers
- Cell therapy and transplantation
- Genetic testing in clinical practice
- Personalized medicine based on biomarkers
- Pharmacogenomics for drug selection
- N-of-1 trials and individualized approaches
- Remote monitoring for movement disorders
- Digital cognitive assessments
- Wearable devices for neurological conditions
- Telemedicine in neurological care
- President's Lecture — Highlights in neurology
- American Brain Foundation Lecture — Research advances
- Neuroscience Education Institute sessions
- "Update on Alzheimer's Disease" — Comprehensive review
- "Parkinson's Disease: From Diagnosis to Treatment"
- "ALS: Current Status and Future Directions"
- "Hot Topics in Neurology" — Late-breaking research
- Clinical examination technique updates
- Neuroimaging interpretation courses
- EEG and EMG workshops
- Botulinum toxin injection training
Located in Center City Philadelphia, the convention center offers:
- Over 500,000 square feet of exhibit space
- State-of-the-art meeting rooms
- Proximity to historic Philadelphia
- Easy access via public transportation
Philadelphia has deep roots in neurology:
- University of Pennsylvania — First neurology department in the US
- Mutter Museum — Historical medical specimens
- American Neurological Association — Founded in Philadelphia
- Multiple teaching hospitals with strong neurology programs
- Philadelphia International Airport (PHL) — Major hub
- Amtrak — Union Station nearby
- Public transit — SEPTA regional rail
- Convention Center — Adjacent to 30th Street Station