V1b receptors are involved in stress response, ACTH release, and emotional processing.
| Property |
Value |
| Category |
Vasopressin Receptor Neurons |
| Location |
Hypothalamus, Pituitary, Amygdala |
| Receptor Type |
V1b (AVPR1B) |
| Signaling |
Gq-coupled, excitatory |
- Family: V1 receptors
- G protein: Gq
- PLC: Activates
- Hypothalamus: PVN
- Pituitary: Anterior
- Amygdala: Corticomedial
- ACTH: Release
- **Cortisol': Stress axis
- **CRH': Interaction
- **Anxiety': Anxiogenic
- **Depression': Role
- **Aggression': Modulation
- V1b: Stress-related
- **Antagonists': Potential
- **SSR149415': Research
- V1b: Anxiogenic
- **Stress': Response
- **Therapeutic': Targeting
- Rabadan-Diehl, V1b in HPA axis (2003)
- Steckler, V1b pharmacology (2005)