Cocaine- and amphetamine-regulated transcript (CART) neurons regulate energy balance and reward.
| Property |
Value |
| Category |
Neuropeptide Neurons |
| Location |
Hypothalamus, Limbic System |
| Cell Type |
CART neurons |
| Neuropeptide |
CART |
- CART 55-102: Active fragment
- CART 62-102: Another active form
- Receptors: Unknown, possibly novel
- Arcuate nucleus: POMC/CART
- Paraventricular nucleus: Stress response
- Nucleus accumbens: Reward
- Anorexigenic: Suppresses appetite
- Leptin signaling: Upstream of CART
- Energy expenditure: Thermogenesis
¶ Reward and Addiction
- Psychostimulant regulation: Cocaine effects
- Dopamine interaction: Reward pathway
- Addiction: CART in drug-seeking
- CART deficiency: Weight gain
- Therapeutic: CART agonists
- Metabolic syndrome: CART role
- CART in addiction: Treatment target
- Relapse: CART modulation
- Rogge. CART peptides (2008)
- Kuhar. CART in addiction (2002)